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Article

The Mutation Hotspots at UGT1A Locus May Be Associated with Gilbert's Syndrome Affecting the Taiwanese Population.

International journal of molecular sciences - 21 Oct 2022

Hsu Paul Wei-Che, Liao Po-Cheng, Kao Yu-Hsiang, Lin Xin-Yu, Chien Rong-Nan, Yeh Chau-Ting, Lai Chi-Chun, Shyu Yu-Chiau, Lin Chih-Lang

Abstract excerpt

Gilbert's syndrome is mainly diagnosed through genetic analysis and is primarily detected through a mutation in the promoter region of the UGT1A1 gene. However, most of the research has been conducted on Caucasian populations. In this study, we studied the Han population in Taiwan to investigate the possibility of other mutations that could cause Gilbert's syndrome. This study comprised a test group of 45...

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Identifiers

PMID: 36293566
DOI: 10.3390/ijms232012709
PMCID: PMC9603874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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