Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in Cancer

23 Mar 2022

Abstract excerpt

Post-translational modifications of proteins ensure optimized cellular processes, including proteostasis, regulated signaling, cell survival, and stress adaptation to maintain a balanced homeostatic state. Abnormal post-translational modifications are associated with cellular dysfunction and the occurrence of life-threatening diseases, such as cancer and neurodegenerative diseases. Therefore, some of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Peptidase Inhibition and Analysis
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35408841
DOI: 10.3390/ijms23073480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in CancerPMID 35408841Read ↗

Ubiquitination and SUMOylation: Protein Homeostasis Control Over CancerSemantic proximity Read ↗

Ubiquitination in cancer: mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatmentSemantic proximity Read ↗

Emerging Roles of Non-proteolytic Ubiquitination in TumorigenesisSemantic proximity Read ↗

RNF4—A Paradigm for SUMOylation‐Mediated UbiquitinationSemantic proximity Read ↗

Unraveling the Potential Role of NEDD4-like E3 Ligases in CancerSemantic proximity Read ↗

The post-translational modification, SUMOylation, and cancer (Review)Semantic proximity Read ↗

Ubiquitin and Ubiquitin-like Proteins in Cancer, Neurodegenerative Disorders, and Heart DiseasesSemantic proximity Read ↗

The implication of the SUMOylation pathway in breast cancer pathogenesis and treatmentSemantic proximity Read ↗

Role of K63-linked ubiquitination in cancerSemantic proximity Read ↗

Deubiquitylating Enzymes in Cancer and ImmunitySemantic proximity Read ↗

Roles of Ubiquitination and SUMOylation on Prostate Cancer: Mechanisms and Clinical ImplicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.