Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study.

doi:10.1200/PO.21.00534

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Article

Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study.

JCO precision oncology - 1 Oct 2022

Ruhen Olivia, Lak Nathalie S M, Stutterheim Janine, Danielli Sara G, Chicard Mathieu, Iddir Yasmine, Saint-Charles Alexandra, Di Paolo Virginia, Tombolan Lucia, Gatz Susanne A, Aladowicz Ewa, Proszek Paula, Jamal Sabri, Stankunaite Reda, Hughes Deborah, Carter Paul, Izquierdo Elisa, Wasti Ajla, Chisholm Julia C, George Sally L, Pace Erika, Chesler Louis, Aerts Isabelle, Pierron Gaelle, Zaidi Sakina, Delattre Olivier, Surdez Didier, Kelsey Anna, Hubank Michael, Bonvini Paolo, Bisogno Gianni, Di Giannatale Angela, Schleiermacher Gudrun, Schäfer Beat W, Tytgat Godelieve A M, Shipley Janet

Abstract excerpt

PURPOSE: Rhabdomyosarcomas (RMS) are rare neoplasms affecting children and young adults. Efforts to improve patient survival have been undermined by a lack of suitable disease markers. Plasma circulating tumor DNA (ctDNA) has shown promise as a potential minimally invasive biomarker and monitoring tool in other cancers; however, it remains underexplored in RMS. We aimed to determine the feasibility of identifying...

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PMID: 36265118
DOI: 10.1200/PO.21.00534
PMCID: PMC9616639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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