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Article

Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriers.

Journal of genetic counseling - 1 Apr 2023

McKenna Danielle B, Sanchez Pauleen, Powers Jacquelyn, Brower Jamie, Wang Louise, Mueller Rebecca, Symecko Heather, Hamilton Jada G, Wildman Temima, Domchek Susan M, Couch Fergus J, Garber Judy E, Offit Kenneth, Robson Mark E, Katona Bryson W

Abstract excerpt

Germline genetic testing for inherited cancer risk is increasingly being performed with multigene panel testing with MUTYH often included on colorectal cancer- and polyposis-focused panels, as well as on broader pan-cancer panels. With up to 1%-2% of the general population being monoallelic MUTYH carriers, pathogenic/likely pathogenic (P/LP) variants in MUTYH are one of the most common findings on multigene...

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Identifiers

PMID: 36245263
DOI: 10.1002/jgc4.1641
PMCID: PMC10436665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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