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Development of a Hallmark Pathway-Related Gene Signature Associated with Immune Response for Lower Grade Gliomas

9 Oct 2022

Abstract excerpt

Although some biomarkers have been used to predict prognosis of lower-grade gliomas (LGGs), a pathway-related signature associated with immune response has not been developed. A key signaling pathway was determined according to the lowest adjusted p value among 50 hallmark pathways. The least absolute shrinkage and selection operator (LASSO) and stepwise multivariate Cox analyses were performed to construct a...

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PMID: 36233273
DOI: 10.3390/ijms231911971

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