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Article

Genetic variation in the ADIPOQ gene and serum adiponectin increase the risk of bladder cancer.

Journal of applied biomedicine - 1 Oct 2022

Elsalem Lina, Alfaqih Mahmoud A, Al Bashir Samir, Halalsheh Omar, Basheer Haneen A, Mhedat Khawla, Khader Yousef, Pors Klaus

Abstract excerpt

Bladder cancer (BC) is the 10th most common cancer worldwide. Genetic studies estimated 30% heritability in BC risk. Adiponectin is an adipocytokine that has important roles in the regulation of energy metabolism. Recent evidence suggests dysregulation of adiponectin levels in BC tissues. Serum level of adiponectin is influenced by single nucleotide polymorphisms (SNPs) in the ADIPOQ gene. However, limited...

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PMID: 36218131
DOI: 10.32725/jab.2022.012

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