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Impaired expression of serine/arginine protein kinase 2 (SRPK2) affects melanoma progression

23 Sept 2022

Abstract excerpt

Melanoma is one of the most aggressive tumors, and its lethality is associated with the ability of malignant cells to migrate and invade surrounding tissues to colonize distant organs and to generate widespread metastasis. The serine/arginine protein kinases 1 and 2 (SRPK1 and SRPK2) are classically related to the control of pre-mRNA splicing through SR protein phosphorylation and have been found overexpressed in...

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PMID: 36212152
DOI: 10.3389/fgene.2022.979735

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