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Article

miR-1306 induces cell apoptosis by targeting BMPR1B gene in the ovine granulosa cells

23 Sept 2022

Abstract excerpt

Bone morphogenetic protein receptor type-1B (BMPR1B) is one of the major gene for sheep prolificacy. However, few studies investigated its regulatory region. In this study, we reported that miR-1306 is a direct inhibitor of BMPR1B gene in the ovine granulosa cells (ovine GCs). We detected a miRNA response element of miR-1306 in the 3' untranslated region of the ovine BMPR1B gene. Luciferase assay showed that the...

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PMID: 36212145
DOI: 10.3389/fgene.2022.989912

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