Article
Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway
27 Jan 2020
Abstract excerpt
Bone morphogenetic proteins (BMPs) are known to play an indispensable role in preventing the precocious luteinization of granulosa cells within growing ovarian follicles. In this study, we found that the transcripts of BMP8 genes are enriched in the ovaries of humans and rodents. When analyzing transcriptomic datasets obtained from human mature granulosa cells, we further found that the BMP8 transcripts not only...
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