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Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer

19 Jun 2025

Abstract excerpt

Recent studies have progressively clarified the critical role of long non-coding RNA (lncRNA) in cancer, especially concerning its involvement in immune processes, which holds significant therapeutic promise. However, the incorporation of lncRNA into immunotherapy has yet to demonstrate adequate clinical efficacy. This shortcoming can be attributed to various challenges, including unclear mechanisms of action and...

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PMID: 40537762
DOI: 10.1186/s12967-025-06732-8

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