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Article

Conservation at the uterine–placental interface

3 Oct 2022

Abstract excerpt

The hemochorial placentation site is characterized by a dynamic interplay between trophoblast cells and maternal cells. These cells cooperate to establish an interface required for nutrient delivery to promote fetal growth. In the human, trophoblast cells penetrate deep into the uterus. This is not a consistent feature of hemochorial placentation and has hindered the establishment of suitable animal models. The...

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PMID: 36191208
DOI: 10.1073/pnas.2210633119

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