A randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis.

doi:10.1038/s41598-022-20818-z

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Article

A randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis.

Scientific reports - 30 Sept 2022

Lorenz Georg, Shen Yuli, Hausinger Renate Ilona, Scheid Caroline, Eckermann Marie, Hornung Sophia, Cardoso Joana, Lech Maciej, Ribeiro Andrea, Haller Bernhard, Holzmann-Littig Christopher, Steubl Dominik, Braunisch Matthias C, Günthner Roman, Poschenrieder Andreas, Freitag Britt, Weber Mario, Luppa Peter, Heemann Uwe, Schmaderer Christoph

Abstract excerpt

Extended cut-off filtration by medium cut-off membranes (MCO) has been shown to be safe in maintenance hemodialysis (HD). The notion of using them for the control of chronic low-grade inflammation and positively influencing cellular immune aberrations seems tempting. We conducted an open label, multicenter, randomized, 90 day 2-phase cross over clinical trial (MCO- vs. high flux-HD). 46 patients underwent...

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PMID: 36180564
DOI: 10.1038/s41598-022-20818-z
PMCID: PMC9524345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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