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Visualized Gallium/Lyticase‐Integrated Antifungal Strategy for Fungal Keratitis Treatment

30 Sept 2022

Abstract excerpt

Fungal keratitis has been one of the common corneal infections that causes blindness, but an effective antifungal strategy remains a challenge. The exopolysaccharides both in the fungal cell walls and biofilms are a key that acts as a permeation barrier to weaken the therapeutic effect of antifungal agents. Herein, lyticase and gallium ions co-integrated nanosystems (MLPGa) are presented that can degrade...

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PMID: 36177690
DOI: 10.1002/adma.202206437

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