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Article

Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling

25 May 2023

Abstract excerpt

Pathophysiological analysis and drug discovery targeting human diseases require disease models that suitably recapitulate patient pathology. Disease-specific human induced pluripotent stem cells (hiPSCs) differentiated into affected cell types can potentially recapitulate disease pathology more accurately than existing disease models. Such successful modeling of muscular diseases requires efficient...

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PMID: 37231024
DOI: 10.1038/s41598-023-34445-9

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