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Exploration of differentially expressed mRNAs and miRNAs for pediatric acute myeloid leukemia

6 Sept 2022

Abstract excerpt

Background: To establish a comprehensive differential gene profile for pediatric acute myeloid leukemia patients (pAML) based on two independent databases and verify the differentially expressed genes using in vitro and in vivo analyses. Methods: The mRNA and miRNA sequencing information of GSE2191 and GSE35320, clinically recruited pAML individuals, and human AML cell line (NB4 cells) were utilized in the study....

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PMID: 36160019
DOI: 10.3389/fgene.2022.865111

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