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The regulatory roles of T helper cells in distinct extracellular matrix characterization in breast cancer

8 Sept 2022

Abstract excerpt

Background: Tumors are characterized by extracellular matrix (ECM) remodeling and stiffening. The ECM has been recognized as an important determinant of breast cancer progression and prognosis. Recent studies have revealed a strong link between ECM remodeling and immune cell infiltration in a variety of tumor types. However, the landscape and specific regulatory mechanisms between ECM and immune microenvironment...

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PMID: 36159822
DOI: 10.3389/fimmu.2022.871742

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