Article
Cross-population genetic analysis revealed genetic variation and selection in the Ovar-DRB1 gene of Indian sheep breeds.
Animal biotechnology - 1 Dec 2023
Gowane G R, Sharma Priya, Kumar Rajiv, Misra S S, Alex Rani, Vohra V, Chhotaray S, Dass Gopal, Chopra Ashish, Kandalkar Yogesh, Vijay V, Choudhary Abhinav, Magotra Ankit, Rajendran R
Abstract excerpt
In sheep, MHC variability is studied widely to explore disease association. The aim of the current study was to explore the genetic diversity of Ovar-DRB diversity across sheep breeds of India. Here, Ovar-DRB1 locus was studied across 20 sheep breeds. DRB1 was amplified (301 bp) and sequenced using a PCR-sequence-based typing approach. Results revealed a high degree of heterozygosity across breeds (mean: 73.99%)....
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