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Exploring genetic diversity and variation of Ovar-DRB1 gene in Sudan Desert Sheep using targeted next-generation sequencing.

BMC genomics - 8 Feb 2024

Salim Bashir, Nakao Ryo, Chatanga Elisha, Marcuzzi Olivia, Eissawi Muna Ahmed, Almathen Faisal, Hanotte Olivier, Giovambattista Guillermo

Abstract excerpt

INTRODUCTION: The Ovar-DRB1 gene, a crucial element of the Major Histocompatibility Complex (MHC) Class II region, initiates adaptive immunity by presenting antigens to T-cells. Genetic diversity in sheep, particularly in MHC Class II genes like Ovar-DRB1, directly influences the specturm of presented antigens impacting immune responses and disease susceptability. Understanding the allelic diversity of Ovar-DRB1...

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Identifiers

PMID: 38331741
DOI: 10.1186/s12864-024-10053-3
PMCID: PMC10851530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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