Article
The Promising Epigenetic Regulators for Refractory Epilepsy: An Adventurous Road Ahead.
Neuromolecular medicine - 1 Jun 2023
Suvekbala Vemparthan, Ramachandran Haribaskar, Veluchamy Alaguraj, Mascarenhas Mariano A Bruno, Ramprasath Tharmarajan, Nair M K C, Garikipati Venkata Naga Srikanth, Gundamaraju Rohit, Subbiah Ramasamy
Abstract excerpt
The attribution of seizure freedom is yet to be achieved for patients suffering from refractory epilepsy, e.g. Dravet Syndrome (DS). The confined ability of mono-chemical entity-based antiseizure drugs (ASDs) to act directly at genomic level is one of the factors, combined with undetermined seizure triggers lead to recurrent seizure (RS) in DS, abominably affecting the sub-genomic architecture of neural cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.