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Article

Determination of Blood NOTCH3 Extracellular Domain and Jagged-1 Levels in Healthy Subjects.

International journal of molecular sciences - 11 Sept 2022

Kim Hyesung, Jang Bogun, Kim Yang-Ji, Choi Jay Chol

Abstract excerpt

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common genetic disorder among those responsible for hereditary strokes, and it is caused by a mutation in the NOTCH3 gene on chromosome 19. Blood biomarkers related to the Notch signaling pathway have not been investigated extensively in CADASIL. In this study, we measured the serum and plasma levels...

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Identifiers

PMID: 36142458
DOI: 10.3390/ijms231810547
PMCID: PMC9505916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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