CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Article

CADASIL: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Journal of neuropathology and experimental neurology - 1 Sept 1997

Ruchoux M M, Maurage C A

Abstract excerpt

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a recently identified cause of stroke and vascular dementia. It is a condition of mid-adulthood due to mutations of Notch 3 gene on chromosome 19. Whereas the disease was first reported in Euro...

Topics

Cerebral Infarction
Cerebrovascular Disorders
Genes, Dominant
Humans
Leukoencephalopathy, Progressive Multifocal
Mutation
Proto-Oncogene Proteins
Receptors, Cell Surface

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