TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway

Abstract excerpt

BACKGROUND: Successful implantation is a complex process that is influenced by embryo quality, endometrial receptivity, immune factors, and the specific type of in vitro fertilization protocol used. DNA topoisomerase IIα (TOP2A) is a well-known protein involved in cell proliferation; however, its expression and effect on the endometrium in recurrent implantation failure (RIF) have not been fully elucidated....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endometriosis Research and Treatment
• Share to Gynecological conditions and treatments
• Share to Reproductive System and Pregnancy