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Article

miR-4478 Accelerates Nucleus Pulposus Cells Apoptosis Induced by Oxidative Stress by Targeting MTH1

20 Sept 2022

Abstract excerpt

OBJECTIVES: Low back pain is the leading cause of disability in the elderly population and is strongly associated with intervertebral disk degeneration (IVDD). However, the precise molecular mechanisms regulating IVDD remain elusive. This study aimed to investigate the role of differentially expressed miRNAs in the pathogenesis of IVDD. MATERIALS AND METHODS: We analyzed miRNA microarray datasets to identify...

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Share to Cervical and Thoracic Myelopathy
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PMID: 36130054
DOI: 10.1097/brs.0000000000004486

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