Article
Mutations in circulating tumor DNA detected in the postoperative period predict poor survival in patients with ovarian cancer.
Biomedical journal - 1 Oct 2023
Chao Angel, Chen Shu-Jen, Chen Hua-Chien, Tan Kien Thiam, Hsiao Wen, Jung Shih-Ming, Yang Lan-Yan, Huang Kuan-Gen, Chou Hung-Hsueh, Huang Huei-Jean, Chang Ting-Chang, Chao An-Shine, Lee Yun-Hsien, Wu Ren-Chin, Lai Chyong-Huey
Abstract excerpt
BACKGROUND: We investigated whether mutations in plasma circulating tumor DNA (ctDNA) can provide prognostic insight in patients with different histological types of ovarian carcinoma. We also examined the concordance of mutations detected in ctDNA samples with those identified in the corresponding formalin-fixed paraffin-embedded (FFPE) tumor specimens. METHODS: Between July 2016 and December 2017, 29 patients...
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