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Determination of double- and single-stranded DNA breaks in bovine sperm is predictive of their fertilizing capacity

17 Sept 2022

Abstract excerpt

BACKGROUND: The analysis of chromatin integrity has become an important determinant of sperm quality. In frozen-thawed bovine sperm, neither the sequence of post-thaw injury events nor the dynamics of different types of sperm DNA breaks are well understood. The aim of the present work was to describe such sperm degradation aftermath focusing on DNA damage dynamics, and to assess if this parameter can predict...

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PMID: 36114517
DOI: 10.1186/s40104-022-00754-8

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