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Article

Deciphering impact of single nucleotide polymorphisms on cotranscriptional modification in CCM gene mRNAs.

American journal of physiology. Cell physiology - 1 Oct 2022

Scimone Concetta, Donato Luigi, Alibrandi Simona, Alafaci Concetta, D'Ascola Angela, Vinci Sergio, D'Angelo Rosalia, Sidoti Antonina

Abstract excerpt

Novel insights on regulation of gene expression mechanisms highlight the pivotal role of epitranscriptomic modifications on decision about transcript fate. These modifications include methylation of adenosine and cytosine in RNA molecules. Impairment of the normal epitranscriptome profile was observed in several pathological conditions, such as cancer and neurodegeneration. However, it is still unknown if...

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PMID: 36094437
DOI: 10.1152/ajpcell.00279.2022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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