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Article

CT imaging phenotypes linked to CA125 and HE4 biomarkers are highly predictive in discriminating between hereditary and sporadic ovarian cancer patients.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2022

Manganaro Lucia, Celli Veronica, Viggiani Valentina, Berardelli Elena, Granato Teresa, Tartaglione Sara, Farina Antonella, Catalano Carlo, Angeloni Antonio, Anastasi Emanuela

Abstract excerpt

BACKGROUND: Hereditary ovarian cancers (HOC) represent about 23% of ovarian cancer (OC) cases: they are most frequently related to germline mutations in the BRCA genes. OBJECTIVE: We aimed to compare CA125/HE4 serum levels and Computed Tomography (CT) features at time of ovarian cancer (OC) diagnosis in two populations: BRCA mutant and BRCA wild-type (WT) OC, and to investigate the relationship between this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36093649
DOI: 10.3233/TUB-211557

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