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Elevated Serum Level of CA125 Is a Biomarker That Can Be Used to Alter Prognosis Determined by BRCA Mutation and Family History in Ovarian Cancer.

Genetic testing and molecular biomarkers - 1 Sept 2017

Liu Weiling, Wang Zhizhong, Ma Jie, Hou Yangyang, Zhao Jiuzhou, Dong Bing, Tu Shichun, Wang Li, Guo Yongjun

Abstract excerpt

AIMS: In this study, we determined whether serum tumor markers (STMs), including CA125, are associated with BRCA mutation status and if they can be used prognostically in sporadic ovarian cancer (SOC) and familial ovarian cancer (FOC). METHODS: BRCA gene mutations were screened using next-generation sequencing (NGS) in 31 FOC and 66 SOC patients enrolled between 2013 and 2014. The serum levels of STM CEA, CA125,...

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Identifiers

PMID: 28799806
DOI: 10.1089/gtmb.2017.0104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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