Article
The roles of intratumour heterogeneity in the biology and treatment of pancreatic ductal adenocarcinoma
10 Sept 2022
Abstract excerpt
Intratumour heterogeneity (ITH) has become an important focus of cancer research in recent years. ITH describes the cellular variation that enables tumour evolution, including tumour progression, metastasis and resistance to treatment. The selection and expansion of genetically distinct treatment-resistant cancer cell clones provides one explanation for treatment failure. However, tumour cell variation need not...
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