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Diagnosis of pathogens causing bacterial meningitis using Nanopore sequencing in a resource-limited setting

5 Sept 2022

Abstract excerpt

AIM: The aim of the present study is to compare the performance of 16S rRNA Nanopore sequencing and conventional culture in detecting infectious pathogens in patients with suspected meningitis in a resource-limited setting without extensive bioinformatics expertise. METHODS: DNA was isolated from the cerebrospinal fluid (CSF) of 30 patients with suspected bacterial meningitis. The isolated DNA was subjected to...

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PMID: 36064402
DOI: 10.1186/s12941-022-00530-6

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