Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differences in Sex-Specific Frequency of Glucocerebrosidase Variant Carriers and Familial Parkinsonism.

Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2022

Ortega Roberto A, Bressman Susan B, Raymond Deborah, Ozelius Laurie J, Katsnelson Viktoriya, Leaver Katherine, Swan Matthew C, Shanker Vicki, Miravite Joan, Wang Cuiling, Bennett Steffany A L, Saunders-Pullman Rachel

Abstract excerpt

BACKGROUND: Although men and women with the LRRK2 G2019S variant appear to be equally likely to have Parkinson's disease (PD), the sex-distribution among glucocerebrosidase (GBA) variant carriers with PD, including limited to specific variant severities of GBA, is not well understood. Further, the sex-specific genetic contribution to PD without a known genetic variant is controversial. OBJECTIVES: To better...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glucosylceramidase
Share to Glycogen Storage Diseases and Myoclonus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Lysosomal Storage Disorders Research

Share to Mutation

Share to Parkinson Disease

Share to Parkinson's Disease Mechanisms and Treatments

Source

Open in PubMed Open full text

Identifiers

PMID: 36054306
DOI: 10.1002/mds.29197
PMCID: PMC9669136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differences in Sex-Specific Frequency of Glucocerebrosidase Variant Carriers and Familial Parkinsonism.PMID 36054306Read ↗

Genetic and phenotypic characterization of Parkinson’s disease at the clinic-wide levelSemantic proximity Read ↗

Mutations in the glucocerebrosidase gene are associated with early-onset Parkinson disease.Semantic proximity Read ↗

Penetrance of Glucocerebrosidase (GBA) Mutations in Parkinson's Disease: A Kin Cohort Study.Semantic proximity Read ↗

Sex distribution and classification of GBA1 variants in an Italian cohort of Parkinson's disease patients analyzed over the last seventeen years.Semantic proximity Read ↗

Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes.Semantic proximity Read ↗

A Global Perspective of GBA1-Related Parkinson's Disease: A Narrative Review.Semantic proximity Read ↗

Association of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression.Semantic proximity Read ↗

GBA-Related Parkinson's Disease: Dissection of Genotype-Phenotype Correlates in a Large Italian Cohort.Semantic proximity Read ↗

Consensus Guidance for Genetic Counseling in GBA1 Variants: A Focus on Parkinson's Disease.Semantic proximity Read ↗

Glucocerebrosidase (GBA) gene variants in a multi-ethnic Asian cohort with Parkinson's disease: mutational spectrum and clinical features.Semantic proximity Read ↗

Shared and Sex-Specific Genetic Risk for Parkinson’s Disease Risk Across European PopulationsSemantic proximity Read ↗

Gender differences in the prevalence of Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.