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Monkeypox DNA levels correlate with virus infectivity in clinical samples, Israel, 2022

1 Sept 2022

Abstract excerpt

The current monkeypox virus global spread and lack of data regarding clinical specimens' infectivity call for examining virus infectivity, and whether this correlates with results from PCR, the available diagnostic tool. We show strong correlation between viral DNA amount in clinical specimens and virus infectivity toward BSC-1 cell line. Moreover, we define a PCR threshold value (Cq ≥ 35, ≤ 4,300 DNA copies/mL),...

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PMID: 36052723
DOI: 10.2807/1560-7917.es.2022.27.35.2200636

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