Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia.

European journal of preventive cardiology - 15 Nov 2022

Paquette Martine, Carrié Alain, Bernard Sophie, Cariou Bertrand, Hegele Robert A, Genest Jacques, Trinder Mark, Brunham Liam R, Béliard Sophie, Baass Alexis

Abstract excerpt

AIMS: Patients with familial hypercholesterolaemia (FH) are at increased risk of cardiovascular disease (CVD) due to extremely high circulating LDL cholesterol (LDL-C) concentrations. Our objective was to study the effect of the type of LDL receptor (LDLR) mutation on the incidence of major adverse cardiovascular events (MACEs). METHODS AND RESULTS: This was a multinational prospective cohort study, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Mutation

Share to Receptors, LDL

Source

Identifiers

PMID: 36047048
DOI: 10.1093/eurjpc/zwac188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of the LDL receptor mutation type on incident major adverse cardiovascular events in familial hypercholesterolaemia.PMID 36047048Read ↗

Impact of variants of uncertain significance of LDL receptor on phenotypes of familial hypercholesterolemia.Semantic proximity Read ↗

Type of LDLR mutation and the pharmacogenetics of familial hypercholesterolemia treatment.Semantic proximity Read ↗

Cardiovascular disease in familial hypercholesterolaemia: influence of low-density lipoprotein receptor mutation type and classic risk factors.Semantic proximity Read ↗

Mutational analysis and genotype-phenotype relation in familial hypercholesterolemia: The SAFEHEART registry.Semantic proximity Read ↗

Influence of LDL-receptor mutation type on age at first cardiovascular event in patients with familial hypercholesterolaemia.Semantic proximity Read ↗

Low-density lipoprotein receptor gene mutations and cardiovascular risk in a large genetic cascade screening population.Semantic proximity Read ↗

Impact of low-density lipoprotein receptor mutational class on carotid atherosclerosis in patients with familial hypercholesterolemia.Semantic proximity Read ↗

LDLR variant classification for improved cardiovascular risk prediction in familial hypercholesterolemia.Semantic proximity Read ↗

Effect of low-density lipoprotein receptor mutation on lipoproteins and cardiovascular disease risk: a parent-offspring study.Semantic proximity Read ↗

LDLR Variant Classification for Improved Cardiovascular Risk Prediction in Familial HypercholesterolemiaSemantic proximity Read ↗

Prevalence of familial hypercholesterolemia phenotype and ten-year risk of cardiovascular events in a working population in primary prevention: The ICARIA study.Semantic proximity Read ↗

Cardiovascular risk in relation to functionality of sequence variants in the gene coding for the low-density lipoprotein receptor: a study among 29,365 individuals tested for 64 specific low-density lipoprotein-receptor sequence variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.