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Article

Effect of low-density lipoprotein receptor mutation on lipoproteins and cardiovascular disease risk: a parent-offspring study.

Atherosclerosis - 1 May 2005

Koeijvoets Kristel C M C, Wiegman Albert, Rodenburg Jessica, Defesche Joep C, Kastelein John J P, Sijbrands Eric J G

Abstract excerpt

Studies on the clinical consequences of different low-density lipoprotein (LDL) receptor genotypes in adult patients have yielded conflicting results. We hypothesized that children with familial hypercholesterolemia (FH) provide a better model to perform genotype-phenotype analyses than adults. We tested this hypothesis and assessed the effect of LDL receptor genotypes on lipoprotein levels and on parental risk...

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Source

Identifiers

PMID: 15823280
DOI: 10.1016/j.atherosclerosis.2004.10.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of low-density lipoprotein receptor mutation on lipoproteins and cardiovascular disease risk: a parent-offspring study.PMID 15823280Read ↗

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