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KIF20A promotes the development of fibrosarcoma via PI3K-Akt signaling pathway

28 Aug 2022

Abstract excerpt

Adult fibrosarcoma is an aggressive subtype of soft tissue sarcoma (STS), in which high expression of KIF20A indicates a poor prognosis. However, the precise role of KIF20A in fibrosarcoma progression remains unknown. In this study, we initially examined KIF20A expression and function in the human fibrosarcoma cell line HT-1080. The results showed that KIF20A was highly expressed in HT-1080, knockdown of KIF20A...

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PMID: 36037925
DOI: 10.1016/j.yexcr.2022.113322

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