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Article

The manual hexadimethrine bromide (Polybrene) test. Effects of serum proteins and practical applications.

Transfusion - 1 Jan 2000

Lalezari P

Abstract excerpt

Serum proteins affect the performance of the manual hexadimethrine bromide (Polybrene) test. Red cells suspended in the low-ionic medium adhere to the surface of test tubes when centrifuged. This adherence is prevented by serum components apoprotein B, fibronectin, von Willebrand factor, or serum diluted less than 75-fold, but not by serum albumin or immunoglobulin fractions. A high concentration of serum reduces...

Topics

Antibody Specificity
Blood Grouping and Crossmatching
Blood Proteins
Coombs Test
Hexadimethrine Bromide
Isoantibodies
Kell Blood-Group System
Phenotype
Polyamines

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 3603657
DOI: 10.1046/j.1537-2995.1987.27487264734.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3603657-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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