Article
Study protocol of brief intervention using gene polymorphism information for excessive drinking among Japanese college students and adults aged 20-30 years: a randomized controlled trial.
Trials - 26 Aug 2022
Owaki Yukiko, Yoshimoto Hisashi, Saito Go, Goto Takahiro, Kushio Satoshi, Nakamura Akihiro, Togo Yusuke, Mori Kazumasa, Hokazono Hideki
Abstract excerpt
BACKGROUND: The alcohol-metabolizing enzyme aldehyde dehydrogenase 2 (ALDH2) is a carcinogenic acetaldehyde-degrading enzyme, and its low activity is a genetic constitution peculiar to East Asians. People with low alcohol dehydrogenase 1B activity (ADH1B*1/*1 genotype) have a high risk of developing head and neck cancer and alcoholism. The study aims to evaluate the effectiveness of brief interventions for...
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