Article
Embryologic Origin of the Primary Tumor and RAS Status Predict Survival after Resection of Colorectal Liver Metastases.
Medicina (Kaunas, Lithuania) - 14 Aug 2022
Alexandrescu Sorin Tiberiu, Dinu Ioana Mihaela, Diaconescu Andrei Sebastian, Micu Alexandru, Pasare Evelina, Durdu Cristiana, Dorobantu Bogdan Mihail, Popescu Irinel
Abstract excerpt
Background and objectives. In colorectal cancers, the embryologic origin of the primary tumor determines important molecular dissimilarities between right-sided (RS) and left-sided (LS) carcinomas. Although important prognostic differences have been revealed between RS- and LS-patients with resected colorectal liver metastases (CLMs), it is still unclear if this observation depends on the RAS mutational status....
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