Article
Costimulatory molecule expression profile as a biomarker to predict prognosis and chemotherapy response for patients with small cell lung cancer.
Cancer immunology, immunotherapy : CII - 1 Mar 2023
Wu Peng, Zhang Zhihui, Yang Zhaoyang, Zhang Chaoqi, Luo Yuejun, Zhang Guochao, Wang Lide, Xue Qi, Sun Nan, He Jie
Abstract excerpt
Owing to the paucity of specimens, progress in identifying prognostic and therapeutic biomarkers for small cell lung cancer (SCLC) has been stagnant for decades. Considering that the costimulatory molecules are essential elements in modulating immune responses and determining therapeutic response, we systematically revealed the expression landscape and identified a costimulatory molecule-based signature (CMS) to...
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