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Integrative analysis of multi‐omics data reveals the heterogeneity and signatures of immune therapy for small cell lung cancer

1 Dec 2021

Abstract excerpt

Small cell lung cancer (SCLC) features with high heterogeneity and poor prognosis. The major treatment strategy for SCLC remains combination chemotherapy over past decades, with only minor improvements.1 And the application of immunotherapy has no impressive benefit for SCLC patients.2 In this study, we identify a novel subtype of SCLC (SCLC-I) with immunosuppressive feature and high genomic instability....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34923768
DOI: 10.1002/ctm2.620

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