Article
Early marker of ocular neurodegeneration in children and adolescents with type 1 diabetes: the contributing role of polymorphisms in mir146a and mir128a genes.
Acta diabetologica - 1 Dec 2022
Piona Claudia, Costantini Silvia, Zusi Chiara, Cozzini Tiziano, Pedrotti Emilio, Marigliano Marco, Fornari Elena, Maguolo Alice, Morandi Anita, Maffeis Claudio
Abstract excerpt
BACKGROUND: Early ocular neurodegenerative signs of diabetic neuropathy (DN) can be found in children and adolescents with type 1 diabetes (T1D). No data are available on the potential role of polymorphisms in miRNAs genes in predisposing T1D subjects to these signs. AIMS: To determine whether MIR146A rs2910164 and MIR128A rs11888095 polymorphisms are associated with early retinal and corneal neurodegenerative...
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