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Article

From bugs to bedside: functional annotation of human genetic variation for neurological disorders using invertebrate models.

Human molecular genetics - 20 Oct 2022

Mew Melanie, Caldwell Kim A, Caldwell Guy A

Abstract excerpt

The exponential accumulation of DNA sequencing data has opened new avenues for discovering the causative roles of single-nucleotide polymorphisms (SNPs) in neurological diseases. The opportunities emerging from this are staggering, yet only as good as our abilities to glean insights from this surplus of information. Whereas computational biology continues to improve with respect to predictions and molecular...

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PMID: 35994032
DOI: 10.1093/hmg/ddac203
PMCID: PMC9585664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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