HNRNPA2B1: RNA-Binding Protein That Orchestrates Smooth Muscle Cell Phenotype in Pulmonary Arterial Hypertension.

Abstract excerpt

BACKGROUND: RNA-binding proteins are master orchestrators of gene expression regulation. They regulate hundreds of transcripts at once by recognizing specific motifs. Thus, characterizing RNA-binding proteins targets is critical to harvest their full therapeutic potential. However, such investigation has often been restricted to a few RNA-binding protein targets, limiting our understanding of their function. In...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Familial Primary Pulmonary Hypertension
• Share to Heterogeneous-Nuclear Ribonucleoproteins