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Article

Mutations in proteins involved in E-C coupling and SOCE and congenital myopathies.

The Journal of general physiology - 5 Sept 2022

Rossi Daniela, Catallo Maria Rosaria, Pierantozzi Enrico, Sorrentino Vincenzo

Abstract excerpt

In skeletal muscle, Ca2+ necessary for muscle contraction is stored and released from the sarcoplasmic reticulum (SR), a specialized form of endoplasmic reticulum through the mechanism known as excitation-contraction (E-C) coupling. Following activation of skeletal muscle contraction by the E-C coupling mechanism, replenishment of intracellular stores requires reuptake of cytosolic Ca2+ into the SR by the...

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Identifiers

PMID: 35980353
DOI: 10.1085/jgp.202213115
PMCID: PMC9391951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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