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Article

Role of cellular senescence in the pathogenesis of systemic sclerosis

16 Aug 2022

Abstract excerpt

PURPOSE OF REVIEW: Systemic sclerosis (SSc) is a chronic rheumatic disease that is characterized by immune activation, vasculopathy and fibrosis of the skin and internal organs. It has been proposed that premature onset of ageing pathways and associated senescent changes in cells contribute to the clinical and pathological features of SSc. The aim of this review is to critically review recent insights into the...

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PMID: 35979691
DOI: 10.1097/bor.0000000000000898

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