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Article

Multiple sclerosis diagnosis and phenotype identification by multivariate classification of in vivo frontal cortex metabolite profiles.

Scientific reports - 16 Aug 2022

Swanberg Kelley M, Kurada Abhinav V, Prinsen Hetty, Juchem Christoph

Abstract excerpt

Multiple sclerosis (MS) is a heterogeneous autoimmune disease for which diagnosis continues to rely on subjective clinical judgment over a battery of tests. Proton magnetic resonance spectroscopy (1H MRS) enables the noninvasive in vivo detection of multiple small-molecule metabolites and is therefore in principle a promising means of gathering information sufficient for multiple sclerosis diagnosis and subtype...

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PMID: 35974117
DOI: 10.1038/s41598-022-17741-8
PMCID: PMC9381573

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