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Article

Tumor mutation burden-assisted risk stratification for papillary thyroid cancer.

Endocrine - 1 Nov 2022

Chen Zhijiang, Wang Weiran, Xu Jiajie, Song Yuntao, Zhu Honglin, Ma Tonghui, Ge Minghua, Guan Haixia

Abstract excerpt

PURPOSE: Although papillary thyroid cancer (PTC) has a low mortality rate, the rate of recurrence remains relatively high. This study aims to develop a molecular signature to predict the recurrence of PTC. METHODS: A total of 333 PTC patients' data from The Cancer Genome Atlas (TCGA) were included. We calculated tumor mutation burden (TMB) and analyzed the mutation status of BRAF and TERT promoter. RESULTS: Tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35962256
DOI: 10.1007/s12020-022-03154-0

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