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Clinical sepsis phenotypes in critically ill COVID-19 patients.

Critical care (London, England) - 9 Aug 2022

Bruse Niklas, Kooistra Emma J, Jansen Aron, van Amstel Rombout B E, de Keizer Nicolette F, Kennedy Jason N, Seymour Christopher, van Vught Lonneke A, Pickkers Peter, Kox Matthijs

Abstract excerpt

BACKGROUND: A greater understanding of disease heterogeneity may facilitate precision medicine for coronavirus disease 2019 (COVID-19). Previous work identified four distinct clinical phenotypes associated with outcome and treatment responses in non-COVID-19 sepsis patients, but it is unknown if and how these phenotypes are recapitulated in COVID-19 sepsis patients. METHODS: We applied the four non-COVID-19...

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Communicable Diseases
COVID-19
Critical Illness
Dexamethasone
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PMID: 35945618
DOI: 10.1186/s13054-022-04118-6
PMCID: PMC9361232

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