The circadian clock mediates daily bursts of cell differentiation by periodically restricting cell-differentiation commitment

Abstract excerpt

Most mammalian cells have an intrinsic circadian clock that coordinates metabolic activity with the daily rest and wake cycle. The circadian clock is known to regulate cell differentiation, but how continuous daily oscillations of the internal clock can control a much longer, multiday differentiation process is not known. Here, we simultaneously monitor circadian clock and adipocyte-differentiation progression...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Circadian rhythm and melatonin
• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Spaceflight effects on biology