Article
Colon specific delivery of miR-155 inhibitor alleviates estrogen deficiency related phenotype via microbiota remodeling.
Drug delivery - 1 Dec 2022
Zhao Lianbi, Zhou Tian, Chen Jianmei, Cai Wenbin, Shi Ruijing, Duan Yunyou, Yuan Lijun, Xing Changyang
Abstract excerpt
Compelling data have indicated menopause-associated increase in cardiovascular disease in women, while the underlying mechanisms remain largely unknown. It is established that changes of intestinal microbiota affect cardiovascular function in the context of metabolic syndrome. We here aimed to explore the possible link between host intestinal function, microbiota, and cardiac function in the ovariectomy (OVX)...
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